Myocardial Functional Decline During Prolonged Ex Situ Heart Perfusion
نویسندگان
چکیده
منابع مشابه
Myocardial perfusion characteristics during machine perfusion for heart transplantation.
BACKGROUND Optimal parameters for machine perfusion preservation of hearts prior to transplantation have not been determined. We sought to define regional myocardial perfusion characteristics of a machine perfusion device over a range of conditions in a large animal model. METHODS Dog hearts were connected to a perfusion device (LifeCradle, Organ Transport Systems, Inc, Frisco, TX) and cold p...
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Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...
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M oday, O cber 9, 2017 is hindered in part by the availability of limbs which can survive a limited amount of time disconnected from the body. Cryobiology is the scientific field which investigates biology at low temperatures. Cryobiologists have long sought to cryopreserve biological samples ranging from single cells to complex organs and whole animals. Vitrification is the transformation of a...
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BACKGROUND Vascularized composite allografts, particularly hand and forearm, have limited ischemic tolerance after procurement. In bilateral hand transplantations, this demands a 2 team approach and expedited transfer of the allograft, limiting the recovery to a small geographic area. Ex situ perfusion may be an alternative allograft preservation method to extend allograft survival time. This i...
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In contrast to conventional static cold preservation (0-4 °C), ex situ machine perfusion may provide better preservation of donor livers. Continuous perfusion of organs provides the opportunity to improve organ quality and allows ex situ viability assessment of donor livers prior to transplantation. This video article provides a step by step protocol for ex situ normothermic machine perfusion (...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2019
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2019.01.076